Advancing targeted in vivo LNPs: Five practical considerations to move from concept to clinic

As genetic medicine advances toward targeted in vivo delivery, developers face new challenges in translating promising concepts into clinical reality. From payload design to conjugation chemistry and analytics, each decision shapes manufacturability, scalability, and regulatory success.

In this webinar, experts from Cytiva will share five practical considerations for teams advancing targeted in vivo LNP programs — covering formulation selection, conjugation and targeting strategies, bioanalytical readiness, process complexity, and the approaches to enable clinical development.

Drawing on experience from ARPA-H-funded initiatives and real-world collaborations, the discussion will explore proven strategies that help innovators anticipate and overcome common development hurdles.

Attendees will walk away with a framework for designing in vivo programs that are technically robust, scalable, and ready for clinical advancement — helping teams accelerate the journey from concept to clinic.