Advancing R&D in Gene Therapy

Gene therapies provide patients with unique treatments for traditionally incurable diseases, particularly in the oncology space. However, the vast complexities of biology and novel nature of this research requires innovative approaches to build a complete picture of disease mechanisms. Join us to explore the current hurdles in gene therapy research and how we as an industry can advance therapies and improve care.

Discussion topics will include:

• Uncovering the influence of tissue architecture on cancer progression, immune infiltration, and therapeutic response by combining histology with spatially resolved whole transcriptome analysis in tissue sections
• Identifying novel and rare cell types and states associated with tumor progression and metastasis that were previously masked by bulk analysis methods
• Investigating how alterations in epigenetic architecture lead to transcriptional heterogeneity, resulting in diversity of cell types, states, and dynamics in the tumor microenvironment
• Optimizing cell and gene therapies with single cell multiomics