Design scalable downstream processes with practical purification and analytical strategies

Downstream process development is rapidly evolving as new modalities, from mAbs to mRNA, viral vectors, and other complex molecules, enter development pipelines. This webinar will share practical strategies and analytical considerations for designing robust, scalable purification processes across diverse molecule types.

Drawing on decades of chromatography innovation and the expertise of our global Fast Trak™ process development (PD) teams, Cytiva speakers will show how we use tools such as our Biacore™ surface plasmon resonance (SPR) system and size-exclusion chromatography with multi-angle light scattering (SEC-MALS) to clarify complex mechanisms, address unpredictable impurities, and overcome challenges that traditional approaches cannot resolve.

You will also hear how the combination of this experience, advanced analytics, and focused knowledge transfer can accelerate development, reduce risk, and help customers build lasting internal capability and true process ownership.

Using case examples spanning proteins, antibodies, nucleic acids, viruses, and vesicles, we will feature common downstream pitfalls and highlight how our integrated chromatography and analytical strengths help avoid them. Whether you are advancing proof of concept or preparing to scale up, you will leave with a clear view of how Cytiva PD, SPR, and chromatography leadership enables efficient, confident downstream development—even for the most complex modalities.

Key Learning Objectives:

Learn practical, scalable approaches for developing chromatography‑based purification processes
Understand how advanced analytical tools such as SPR (Biacore™ system) and SEC‑MALS reveal complex molecular interactions and impurity mechanisms
Explore how combining chromatography expertise, advanced analytics, and structured knowledge transfer accelerates development and builds long‑term process capability