From Insights to Impact: Predictive Models and PAT for More Efficient and Robust Biologics Manufacturing

Explore how data-driven tools and Process Analytical Technology (PAT) can optimize scale-up, enhance process control, and reduce risk from cell culture through drug product. Learn how integrating advanced modeling and real-time monitoring enables more reliable, cost-effective, and scalable biologics production.

Key takeaways include:
– Applying predictive, engineering-driven models to improve bioreactor scale-up and performance
– Using mechanistic models and data to enable robust tech transfer and process optimization
– Leveraging PAT tools for real-time monitoring, adaptive control, and process stability
– Scaling lyophilization with design space approaches to ensure product quality and consistency
– Reducing scale-up uncertainty and accelerating path to commercial manufacturing