PBSS Free Online Workshop: Antibody-Drug Conjugates: Discovery to Development

Antibody-drug conjugates harness both the potent activity of a small molecule and the selectivity of a monoclonal antibody. This class of molecules has exploded in interest and success in recent years with >80 molecules undergoing clinical evaluation and 5 new ADCs approved since mid-2019. The workshop will provide the most recent learnings and critical aspects of the discovery and development for this class of bioconjugates.

Workshop Outline
– Chemistry & Conjugation
– Small molecule DMPK for ADCs
– Dose optimization for ADCs
– CMC Challenges and Opportunities in ADC Drug Development
– ADC Safety/Toxicity