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PBSS Online Symposium: Preclinical Models to Guide Therapeutic Development in Oncology – Day 1

December 8, 2020

Speakers: Mark Merchant (Genentech), Maryland Franklin (Covance Preclinical Oncology), Karen Rex (Amgen), Willem Overwijk (Nektar Therapeutics), Shelley Ackerman (Bolt Biotherapeutics)
Organizers: Gregory Wagner and Betty Chang
Time: 8:45-13:00 Pacific Time
Registration fee: (USD):
Location: Online via Zoom
Major Sponsor:
Vendor show vendors registered to date:
Registration: http://www.PBSS.org
Registration deadline:2020-12-07  (it will close sooner if the seating cap is reached)

About the Topic

Day 1: December 08, 2020 –   In Vivo Models and Case Studies with Targeted Therapeutics

  • Symposium Overview and Relevance to Contemporary Issues in Development of Therapeutic Agents for Oncology (Mark Merchant, Genentech)
  • Preclinical Mouse Models for Oncology and Immuno-oncology Applications (Maryland Franklin, Covance-Preclinical Oncology)
  • Preclinical Development of AMG 510, a First-in-human Covalent Inhibitor of KRASG12C for the Treatment of Advanced Solid Tumors (Karen Rex, Amgen)
  • Preclinical Investigation of NKTR-255, a Polymer Conjugated IL-15 with Potent NK cell Activation and anti-tumor activity in combination with tumor targeting antibodies (Willem Overwijk, Nektar Therapeutics)
  • Case Study: Bench to Bedside with Immune Stimulating Antibody Conjugates (ISAC) (Shelley Ackerman, Bolt Biotherapeutics)


December 8, 2020