Developing robust cell harvest and media exchange processes is often complex, particularly when moving from development to GMP manufacturing. Differences in equipment, scale, and automation can introduce variability and delay clinical timelines. Common methods such as TFF face challenges in maintaining consistent parameters during scale-up, while disc-stack centrifugation lacks scale-down models and can expose cells...

Study design is increasingly empowered by a rich and diverse array of data. New sources continue to emerge, fueled by advances in AI that enable the integration of information from literature, ClinicalTrials.gov, digitized protocols, and beyond. Harnessing these complementary data streams allows researchers to design studies that are not only operationally efficient but also more...

Join Drug Delivery Leader's Chief Editor Tom von Gunden as he engages drug delivery experts Beate Bittner, Shannon Hoste, Jonathan Amaya-Hodges, and Fran DeGrazio in a discussion of innovations and advances in injectable, infusible, and implantable devices, systems, platforms, and combinations. Focusing on unmet patient needs and expanded therapeutic targets, the panel will discuss approaches...

Watch industry experts share practical guidance on how to evaluate CDMOs beyond the basics—focusing on experience, talent, and technologies that align with your development goals. Speakers: Jana Spes, CEO & Co-founder, JT Biopharma Partners Peter Bigelow, CEO & Co-founder, SCmple Solutions Christine Sheaffer, Manufacturing & Supply Consultant, Executive Leader Biotech Industry Jeff Buguliskis, PhD, Chief...

Ultrafiltration/Diafiltration (UF/DF) processes that look robust at the development scale often expose critical weaknesses during scale-up or tech transfer—resulting in capacity constraints, excessive manual intervention, delayed timelines, or manufacturing risk. In many cases, these issues trace back to early UF/DF decisions that seemed reasonable at the time but didn’t fully account for scalability, system design,...

Bioprocess Online's Bio-Expo Live is back with its series of live virtual events designed to empower biopharma professionals. Through these sessions, attendees will have the chance to explore the newest equipment and solutions offered by our presenters, aimed at addressing the current challenges within the drug development process. This interactive online platform ensures convenience and...