From Variable to Predictable: How Intensified Upstream Processing Improves Scale-Up and Tech Transfer

As biomanufacturers face increasing pressure to boost productivity, reduce costs, and accelerate timelines, traditional scale-up approaches can introduce variability and performance drift. Intensified upstream processing offers a more scalable, efficient path forward—helping maintain product quality, process stability, and regulatory compliance from development through GMP manufacturing.

In this webinar, Thermo Fisher Scientific experts share best practices and real-world insights on implementing intensified upstream strategies, supported by advanced automation, process analytical technologies (PAT), and data-driven control.

In this session, you will learn how to:
~ Drive productivity with intensification strategies
~ Accelerate timelines using high-density inoculation and optimized seed trains
~ Increase output through perfusion and hybrid processing models
~ Improve consistency with automation, PAT, and real-time control
~ Enable reliable scale-up with standardized tech transfer approaches

Key challenges addressed:
~ Performance drift and variability during scale-up
~ Limited productivity with traditional processes
~ Long development and seed train timelines
~ Inconsistent results across sites

Discover how intensified upstream processing can help you scale with confidence while improving efficiency, consistency, and speed across your operations.